#Data table for symetric interior loops of size 2
#Free energies at 37 degrees for RNA
#Data Arrangement:
#For the 4x4 tables, each starting pair needs its own table.
#This is the AA table:
# 5' --> 3'
# X
# A A
# U U
# Y
# 3' <-- 5'
# Y->
# ----------------------------
# (X) A C G U
# | ----------------------------
# V
# (A) 1.9 1.9 1.9 1.9
# (C) 1.9 1.9 1.9 1.9
# (G) 1.9 1.9 -0.7 1.9
# (U) 1.9 1.9 1.9 1.5
#An energy of "." is "infinity," i.e. not allowed.
# 5' --> 3'
X
A A
U U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.5
# 5' --> 3'
X
A C
U G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 0.8
# 5' --> 3'
X
A G
U C
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 0.8
# 5' --> 3'
X
A U
U A
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.2
# 5' --> 3'
X
A G
U U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.6
# 5' --> 3'
X
A U
U G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.2
# 5' --> 3'
X
C A
G U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.2
# 5' --> 3'
X
C C
G G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 0.9 -0.4 0.5 0.5
C 0.3 0.5 0.5 0.6
G -0.1 0.5 -2.2 0.5
U 0.5 0.0 0.5 -0.1
# 5' --> 3'
X
C G
G C
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 0.9 0.5 0.5 0.5
C 0.5 0.5 0.5 0.5
G 0.5 0.5 -1.4 0.5
U 0.5 0.5 0.5 0.4
# 5' --> 3'
X
C U
G A
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 0.8
# 5' --> 3'
X
C G
G U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 2.2 1.3 1.2 1.2
C 1.2 1.7 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.1
# 5' --> 3'
X
C U
G G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 0.6 0.5 1.2 1.2
C 1.2 1.2 1.2 1.2
G -0.2 1.2 -1.4 1.2
U 1.2 1.0 1.2 1.1
# 5' --> 3'
X
G A
C U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.2
# 5' --> 3'
X
G C
C G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 0.8 0.5 0.5 0.5
C 0.5 0.5 0.5 0.5
G 0.5 0.5 -2.3 0.5
U 0.5 0.5 0.5 -0.6
# 5' --> 3'
X
G G
C C
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 0.9 0.3 -0.1 0.5
C -0.4 0.5 0.5 0.0
G 0.5 0.5 -2.2 0.5
U 0.5 0.6 0.5 -0.1
# 5' --> 3'
X
G U
C A
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 0.8
# 5' --> 3'
X
G G
C U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.6 1.2 1.0 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 0.7
# 5' --> 3'
X
G U
C G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.2 1.5 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.5
# 5' --> 3'
X
U A
A U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.7
# 5' --> 3'
X
U C
A G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.2
# 5' --> 3'
X
U G
A C
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.2 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.2
# 5' --> 3'
X
U U
A A
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.5
# 5' --> 3'
X
U G
A U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.9
# 5' --> 3'
X
U U
A G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.6
# 5' --> 3'
X
G A
U U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.6
# 5' --> 3'
X
G C
U G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.5 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.5
# 5' --> 3'
X
G G
U C
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 0.6 1.2 -0.2 1.2
C 0.5 1.2 1.2 1.0
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.1
# 5' --> 3'
X
G U
U A
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.2
# 5' --> 3'
X
G G
U U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.6
# 5' --> 3'
X
G U
U G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.2
# 5' --> 3'
X
U A
G U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.9
# 5' --> 3'
X
U C
G G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.6 1.2 1.2 1.2
C 1.2 1.2 1.2 1.2
G 1.0 1.2 -1.4 1.2
U 1.2 1.2 1.2 0.7
# 5' --> 3'
X
U G
G C
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 2.2 1.2 1.2 1.2
C 1.3 1.7 1.2 1.2
G 1.2 1.2 -1.4 1.2
U 1.2 1.2 1.2 1.1
# 5' --> 3'
X
U U
G A
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.6
# 5' --> 3'
X
U G
G U
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.9
# 5' --> 3'
X
U U
G G
Y
# 3' <-- 5'
# Y
# ----------------------------
A C G U
# ----------------------------
A 1.9 1.9 1.9 1.9
C 1.9 1.9 1.9 1.9
G 1.9 1.9 -0.7 1.9
U 1.9 1.9 1.9 1.6